Skin-Cap
Information about the infamous psoriasis product, Skin-Cap, and its manufacturer.
Much has been written about Skin-Cap already. To summarize, Skin-Cap was sold from Spain as a psoriasis treatment containing zinc pyrithione (ZnP), but due to its quick effectiveness (ZnP isn’t known to be effective for psoriasis), and its side effect profile, some physicians suspected that it actually contained a potent steroid. When it was tested, by several independent labs, steroids were found. The manufacturer denied that the product contained steroids, and that denial (in light of the lab findings) is the basis of the FDA putting an import ban in place.
Canada gave the product a second chance, over two years after its initial ban, and ended up banning it a second time, due to the presence of another steroid in the product.
Several European countries also have bans of various sorts in place. Skin-Cap was actually banned first in Europe — Spain to be precise, and ironic in a way — years before it was banned by the FDA. At least four different steroids have been found in various versions of the product over the years. At first, Cheminova International (the manufacturer) simply denied the presence of steroids. After rumours started flying, they stopped responding to the question at all, even to people who had partnered with the company.
Obvious myths you might hear (or read) from promoters of Skin-Cap:
We sell the original formula.
Since so many different steroids have been detected over the years, how do they know?
It works because of the special zinc formula.
ZnP has never been shown to work any better than placebo for psoriasis, no matter how it was formulated. Some tests have shown a complete absence of ZnP in Skin-Cap. The claim is basically ad copy which is more than 5 years old.
There are no side effects.
Since they really don’t know what’s in Skin-Cap, how do they know?
There have never been any side effects reported.
This is absolute nonsense — see resources below.
There have never been any lawsuits.
Again, rubbish.
The testing was invalid.
A typical excuse, but it requires that all of the labs around the world which have tested the product be completely clueless about how to accurately test for the presence of a steroid.
A person should also be aware of what “Noble Formula” means. Noble Formula 1 (NF-1) is, basically, the closest guess as to what was in Skin-Cap, including the super-potent steroid. Some companies call this “Noble Formula Rx” to indicate its prescription-only status. NF-1, to be legally created, must be compounded by a pharmacy with a valid prescription and labeling instructions. Noble Formula 2 (NF-2) is the best guess as to what was in Skin-Cap except for the steroid. NF-2 products are available over-the-counter.
It should also be noted that the FDA has made it clear that no product which claims it contains ZnP as its only active ingredient can be sold as a treatment for psoriasis. There are also a number of “clones” out on the market with similar names and/or claims (such as Blue Cap, Zinc Cap, Skin-Zinc, etc.).
Please see Ed Anderson’s Skin-Cap FAQ for highly detailed information.
Links
Food and Drug Administration:
June 18, 1997: Warning Letter to Cheminova America
June 18, 1997: Warning Letter to Nova Medical Corporation
March 4, 1998: Warning Letter to Cheminova International
October 2, 2009: Import Alert #61-06
Health Canada:
World Health Organization:
September 19, 1997: Information Exchange System Alert #64
WHO Drug Information, Volume 11, Number 4, 1997
WHO Drug Information, Volume 11, Number 4, 1997
Dermatology Online Journal:
(11a) Editorial Comment (1997, No. 2)
(11b) Immediacy Is Both a Liability and an Asset of the Internet
(11c) Skin Cap: What Have We Learned, and When Did We Learn It?
(11d) Pustular Psoriasis and Hepatotoxicity Associated with use of Skin Cap Spray
(11e) Skin Cap Spray and Corticosteroids
(11f) Reply by Charles Crutchfield MD
(11g) Skin Cap Analysis in Spain
Advances in Psoriasis Treatment 6(1):4
Discussion Group Archives
(11b) Immediacy Is Both a Liability and an Asset of the Internet
(11c) Skin Cap: What Have We Learned, and When Did We Learn It?
(11d) Pustular Psoriasis and Hepatotoxicity Associated with use of Skin Cap Spray
(11e) Skin Cap Spray and Corticosteroids
(11f) Reply by Charles Crutchfield MD
(11g) Skin Cap Analysis in Spain
Advances in Psoriasis Treatment 6(1):4
Discussion Group Archives
National Psoriasis Foundation:
March 29, 2000: Skin-Cap Pulled from Canadian Market for Second Time
November/December 2000: FDA Investigating Blue Cap
November/December 2000: FDA Investigating Blue Cap
Other:
Clinical Trial on the Efficacy of SKIN-CAP in Vulgar Psoriasis and Seborheic Dermatitis
Sandy Cormack talks a bit about Skin-Cap
July 2002: Flake HQ
Injuryboard.com
July 22/29, 1998: JAMA Letters
Prurigo Nodularis Support Group Messages from May, 2002 and more here
The Skin-Cap Story (a timeline of events from the early 1980s to September of 1997, from the Skin Therapy Letter)
The Temporal Dermatohistopathologic Examination of Human Psoriatic Skin Treated with a Novel Topical Liquid Formulation Containing Clobetasol Propionate by Charles E. Crutchfield III, MD
VOY Forum Messages
Sandy Cormack talks a bit about Skin-Cap
July 2002: Flake HQ
Injuryboard.com
July 22/29, 1998: JAMA Letters
Prurigo Nodularis Support Group Messages from May, 2002 and more here
The Skin-Cap Story (a timeline of events from the early 1980s to September of 1997, from the Skin Therapy Letter)
The Temporal Dermatohistopathologic Examination of Human Psoriatic Skin Treated with a Novel Topical Liquid Formulation Containing Clobetasol Propionate by Charles E. Crutchfield III, MD
VOY Forum Messages
Sales
Advanced Alternatives Center
Beautyworks.com
European Solutions
Med Marketing, LLC
Psoriasis-Solution.net
Skin Cap Products
SkinCap.biz
Skincappsoriasis.co.uk (sister site to beautyworks.com)
Unique Image
VNF Nutrition
Beautyworks.com
European Solutions
Med Marketing, LLC
Psoriasis-Solution.net
Skin Cap Products
SkinCap.biz
Skincappsoriasis.co.uk (sister site to beautyworks.com)
Unique Image
VNF Nutrition
Clones: